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Título del libro: Principles Of Neuro-Oncology: Brain & Skull Base
Título del capítulo: Chemotherapy for brain tumors

Autores UNAM:
JORGE ADAN ALEGRIA BAÑOS;
Autores externos:

Idioma:

Año de publicación:
2020
Palabras clave:

Anterior clinoid; Brain tumors; Glioblastoma; MGMT; RANO criteria; Temozolomide


Resumen:

Gliomas are the most common type of primary malignant brain tumors in adults. They account for 80% of cases. These tumors have been classified by the World Health Organization (WHO), within a four-degree system. Glioblastoma (GB) is the most frequent type of glioma and is associated with a poor prognosis (WHO grade IV). The treatment for these malignancies requires a multimodal work team, which includes chemotherapy and radiotherapy. However, despite the available treatments, life expectancy is short. Recently, with the innovation of imaging studies, better molecular characterization of these malignancies, in addition to new treatments such as immunotherapy, their prognosis will be better. This review will focus primarily on glial tumors and primary CNS lymphoma, their diagnostic approach and current treatment. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2021. All rights reserved.


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