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Título del libro: Epigenetics In Plants Of Agronomic Importance: Fundamentals And Applications: Transcriptional Regulation And Chromatin Remodelling In Plants: Second Edition
Título del capítulo: Targeted epigenome editing of plant defense genes via CRISPR activation (CRISPRa)

Autores UNAM:
JUAN CARLOS VIZUET DE RUEDA;
Autores externos:
Idioma:
Inglés
Año de publicación:
2019
Resumen:

Crop protection plays a central role in maintaining and increasing crop productivity. Many pathogens continue to affect crop production, however, and losses generated by pests must be halted. Thus, if farming is to support the human population, additional viable strategies for crop production and improved integrated pest management systems must be developed. Genome editing is an alternative to conventional breeding that can facilitate the molecular breeding of crops with desired properties. We propose here the implementation of targeted modification of epigenetic marks (epigenome editing via CRISPR activation or CRISPRa) to activate plant defense genes to confer resistance against pathogen attack. Work on CRISPRa in plants is lacking, although its potential application to crops is one of the greatest challenges in the field. Future exploitation of this approach in crop improvement programs will reduce important economic losses and benefit society. © Springer Nature Switzerland AG 2019.

Entidades citadas de la UNAM:
Fuente:


ISBN:
9783030147600
Editorial:
Springer International Publishing Nombre de la publicación:
Targeted epigenome editing of plant defense genes via CRISPR activation (CRISPRa)
Página inicial:
267
Página final:
289

Tipo de producto:
Capítulo de un Libro



DOI:
10.1007/978-3-030-14760-0_10