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Título del libro: Biology Of Domestic Animals
Título del capítulo: Growth hormone and the chick eye

Autores UNAM:
CARLOS GUILLERMO MARTINEZ MORENO;
Autores externos:

Idioma:
Inglés
Año de publicación:
2017
Resumen:

The chick embryo is a classical model to study eye development (Adler and Canto-Soler, 2007; Belecky-Adams et al., 2008; Goodall et al., 2009; Vergara and Canto-Soler, 2012). As pituitary growth hormone (GH) is an established growth factor (Harvey, 2013), it was tacitly assumed that it was causally involved in embryogenesis and eye growth. This belief was, however, re-evaluated with the realization that embryogenesis was a growth- without GH syndrome (Geffner, 1996) and that pituitary somatotrophs only arise ontogenetically during the last trimester of incubation (Harvey et al., 1998), after the completion of approximately 40 of the 46 Hamilton and Hamburger stages of development (Figure 1) (Hamburger and Hamilton, 1951). Nevertheless, with the demonstration that GH gene expression is not confined to pituitary somatotrophs and occurs widely in extrapituitary tissues (Figure 2) (Harvey, 2010), it is likely that GH is involved in the embryogenesis and eye growth as a local autocrine or paracrine factor (Harvey and Baudet, 2014). © 2017 by Taylor & Francis Group, LLC.


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