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Título del libro: Proceedings Of The 2013 Spanish Conference On Electron Devices, Cde 2013
Título del capítulo: Microfluidics applied to Love-wave devices to detect biological warfare agents in dynamic mode

Autores UNAM:
DANIEL MATATAGUI CRUZ;
Autores externos:

Idioma:
Inglés
Año de publicación:
2013
Palabras clave:

Acoustic wave sensors; Biological warfare agents; Fast response; Immunodetection; Love wave; Microfluidic chip; Polyclonal antibody; Short response time; Acoustics; Biosensors; Chemical detection; Chemical warfare; Electron devices; Microfluidics; Monoclonal antibodies; Biological warfare


Resumen:

A Love-wave device combined with a microfluidic chip of PDMS has been developed to detect biological warfare agents (BWA) in liquid media. It has been tested with the realization of two immunoassays: in the first one the bacteriophage M13 has been detected through the mouse monoclonal antibody, anti-M13 (AM13) and in the second one the detection has been carried out by means of the immunoreaction of the rabbit immunoglobulin (Rabbit IgG) with the goat anti-rabbit polyclonal antibody (GAR). The detections have been performed in a dynamic mode (continuous flow-through) in order to obtain a short response time. Different concentrations have been detected with a fast response and a good discrimination among them. © 2013 IEEE.


Entidades citadas de la UNAM: